John D. Rioux, PhD 

 

 

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Mr. Rioux is a Full Professor of Medicine at the Université de Montréal and is holder of the Canada Research Chair in Genetics and Genomic Medicine. He is also a senior researcher at the Montreal Heart Institute and Director of its Integrative Biology Platform (www.medgeni.org).

 

He has been at the forefront of genomics and genetics of rare (monogenic) and common (multigenic) human diseases. He contributed to the first SNP map of the human genome and to mapping the fine haplotype structure of the human genome. He has been a leader in gene identification for chronic inflammatory diseases (including Crohn’s disease, Ulcerative Colitis, Lupus, and multiple sclerosis) using genome-wide association approaches.  He is also a founding member of a number of international genetics consortia. 

 

His current research uses a combination of genetic, genomic and integrative biology approaches in order to provide a more in-depth biologic understanding to these recent genetic discoveries and to develop bioassays based on these findings that can be integrated into prospective clinical trials and address the issue of biological heterogeneity in patient cohorts.

 

The ultimate goal of this work is to identify potential targets for novel therapies and to develop multiplatform predictors of response to therapy. His work is supported by the NIH (NIDDK), CIHR, CFI, Genome Canada, Génome Québec and Crohn’s Colitis Canada.